Search on: RECEPTOR, IGF TYPE 1 
Descriptors Found: 1
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Descriptor English:   Receptor, IGF Type 1 
Descriptor Spanish:   Receptor IGF Tipo 1 
Descriptor Portuguese:   Receptor IGF Tipo 1 
Synonyms English:   IGF 1 Receptor
IGF I Receptor
IGF Type 1 Receptor
IGF-1 Receptor
IGF-1 Receptors
IGF-I Receptor
Insulin Like Growth Factor I Receptor
Insulin-Like-Growth Factor I Receptor
Receptor, IGF I
Receptor, IGF Type 1 alpha Subunit
Receptor, IGF Type 1 beta Subunit
Receptor, IGF-1
Receptor, IGF-I
Receptor, Insulin-Like Growth Factor I
Receptor, Insulin-Like Growth Factor Type 1
Receptors, IGF 1
Receptors, IGF-1
Receptors, Insulin-Like-Growth Factor I  
Tree Number:   D08.811.913.696.620.682.725.400.185
D12.776.543.750.630.468
D12.776.543.750.750.400.780.400
Definition English:   A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain. 
See Related English:   Insulin-Like Growth Factor I
Insulin-Like Growth Factor II
 
History Note English:   2000(1993); 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30558 
Unique Identifier:   D017526 

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